Mounjaro (tirzepatide)

The mechanism of action of Mounjaro (tirzepatide) mimics the effects of the hormones GIP and GLP-1.
Mounjaro (tirzepatide) is the first medication that activates two receptors (dual receptor):

GLP-1 (Glucagon-Like Peptide-1)
Slows down digestion, reduces appetite, and increases feelings of fullness.

GIP (Glucose-Dependent Insulinotropic Polypeptide)
Enhances insulin effectiveness and amplifies the effects of GLP-1 in controlling blood sugar and weight.

Both of these hormones are incretinshormones released by the body after eating.
They help regulate blood glucose levels, satiety, and energy metabolism.

Effects of Mounjaro (Tirzepatide) on Hunger and Satiety
GLP-1 Slows gastric emptying, prolongs satiety, and reduces appetite.
GIP Improves insulin sensitivity and enhances the action of GLP-1.

Effects of Mounjaro (Tirzepatide) on Blood Sugar Control
Promotes appropriate insulin release when blood sugar levels are high.
Reduces secretion of glucagon (a hormone that raises blood sugar).
Suitable for individuals with pre-diabetes or type 2 diabetes.

Effects of Mounjaro (Tirzepatide) on the Brain (Satiety Center)
Tirzepatide stimulates the hypothalamus, the brains center for hunger and satiety.
Reduces cravings and reward responses to foods like sweets or fatty meals.

Effects of Mounjaro (Tirzepatide) on Energy Metabolism
Promotes increased fat burning.
Helps preserve lean muscle mass while reducing body fat (as shown in some studies)

The Mounjaro (tirzepatide) injection pen comes in six dosage strengths, designed to be adjusted gradually according to your doctors treatment plan. This step-up dosing schedule helps your body adapt safely and minimizes side effects.

The pen allows precise dose selection using a rotating click mechanism.
Each click corresponds to a specific amount of medication, making it easier to calculate and administer the correct dose under medical supervision.

Available pen doses:

2.5 mg
5 mg
7.5 mg
10 mg
12.5 mg
15 mg

How to Start Using Mounjaro (tirzepatide) for Weight Loss

When starting Mounjaro (tirzepatide), the dosage should be increased gradually according to a treatment plan. This allows your body to adjust smoothly and helps reduce potential side effects.

Typical starting schedule:

Weeks 14: Begin with 2.5 mg once weekly.
After this, the dose can be gradually increased to 5 mg, 10 mg, and higher over time if needed.
All dose adjustments should be made under medical supervision so your doctor can monitor your progress, manage side effects, and tailor the treatment to your individual needs.